Active skincare ingredients
  • Hydroxypinacolone Retinoate
  • Shaanxi Huatai Bio-Fine Chemicals Co., Ltd

Hydroxypinacolone Retinoate

The Advanced Direct-Binding Retinoid for Non-Irritating Anti-Aging Results

Hydroxypinacolone Retinoate (HPR) is a cutting-edge cosmetic grade ester of All-Trans Retinoic Acid. Unlike traditional Retinol, HPR binds directly to retinoid receptors without the need for metabolic conversion, delivering the powerful anti-aging benefits of Vitamin A with exceptional stability and a significantly lower irritation profile.

CAS No.

893412-73-2

Source

High-Purity Cosmetic Synthesis

Appearance Color

Yellow to Orange Liquid (10% Solution) / Crystalline Powder

Key Parameter

Direct Receptor Binding / High Photostability

Solubility

Oil-Soluble

Direct Factory Supply

Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.

Flexible OEM/ODM

Custom specifications for purity, solvent, and formulation tailored to your requirements.

Stable Supply Chain

Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.

Strict QA & Certs

ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.

The Ultimate 100% Farnesol-Free Hydroxypinacolone Retinoate (HPR): Custom-Engineered for Extremely Sensitive Skin & Zero Sensitization

Clinically proven to reduce skin sensitivity markers by 40% within 48 hours, while delivering a visible reduction in wrinkle depth and a significant increase in skin elasticity within just 2 to 4 weeks of consistent use.

In the advanced landscape of dermatological anti-aging, delivering retinoic acid-like efficacy without triggering the severe irritation, redness, and peeling typical of traditional retinoids is the ultimate formulation challenge. As a specialized high-purity cosmetic active ingredient manufacturer, Shaanxi Huatai Bio-Fine Chemicals Co. delivers a premium Hydroxypinacolone Retinoate (HPR) rigorously engineered to completely remove impurities. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization. By directly binding to Retinoic Acid Receptors (RARs) without requiring any irritation-prone conversion steps, it safely accelerates cell renewal and collagen synthesis, providing professional “A-Grade” anti-wrinkle results for even the most hyper-reactive skin.

Unlocking Unmatched Business Value

For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and extreme compatibility. Our highly purified HPR integrates flawlessly into oil-based and emulsion systems, yielding a highly refined, water-white, and entirely odorless profile. It ensures zero formula discoloration and guarantees it will never compromise the precise color, fragrance, or aesthetic of your final product. Exceptionally stable against oxidation and thermal degradation compared to standard Retinol, it completely eliminates manufacturing friction, complex encapsulation requirements, and stability nightmares for your R&D teams.

For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure, next-generation retinoid is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” formulations. Empower your brand to market “Direct-Acting Anti-Aging” and “Sensitive-Safe Retinoid” lines suitable for both day and night use. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing clinical solutions that deliver rapid texture refinement, melanin inhibition, and deep structural repair without the downtime of traditional Vitamin A derivatives.

Product Overview & Core Specifications

  • Appearance: Available as 99% Pure Powder or 10% Cosmetic Solution (Yields a clear, water-white, odorless profile in formulation)

  • Odor: Odorless (scent neutral)

  • Active Content: 99% Pure Powder or 10% Cosmetic Solution (HPR10)

  • Heavy Metals: < 10 ppm

  • Recommended Usage: 0.1% – 2.0% (for the 10% solution) / 0.01% – 0.1% (for pure powder)

  • pH Range Stability: Best maintained within a pH range of 5.0 – 7.0 for optimal formulation integrity

  • Processing Guidelines: Oil-soluble. Add to the oil phase or at the end of the formulation process below 40°C to maintain peak biological activity and stability.

Ready-to-Use Solutions: The Golden Synergies

Provide your R&D laboratory with an instant blueprint for market success. Our HPR acts as a supreme biological renewal engine, protecting and amplifying the restorative efficacy of companion actives:

  • HPR + Allantoin: The ultimate gentle renewal and cellular clearing matrix. Combines the direct RAR activation and epidermal turnover of HPR with the water-soluble wound-healing properties of Allantoin to rapidly smooth texture, clear acne-prone pores, and instantly soothe any potential micro-traumas from accelerated exfoliation.

  • HPR + Panthenol: A comprehensive “SOS Barrier Rescue” and anti-aging system. Panthenol floods the newly renewed epidermis with deep, targeted hydration, creating a healthy, non-reactive environment that allows HPR to effectively stimulate collagen synthesis and normalize keratinization without triggering dryness or flakiness.

  • HPR + Ceramide NP: The absolute structural longevity and “A-Grade” repair complex. While HPR works fundamentally from within to reduce fine lines and interrupt pigment production, Ceramide NP safely and physically rebuilds the skin’s depleted lipid cement on the surface, ensuring a resilient, youthful, and perfectly protected skin barrier that effortlessly tolerates high-efficacy retinoid treatment.

Uncompromising Quality Assurance

Formulate with absolute regulatory confidence. We strictly adhere to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:

  • ISO9001

  • ISO22000

  • COSMOS

  • HALAL

Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.

Frequently Asked Questions (FAQ)

QuestionAnswer
What is Hydroxypinacolone Retinoate (HPR) and how does it compare to standard Retinol?Hydroxypinacolone Retinoate (HPR) is a next generation cosmetic retinoid that binds directly to skin receptors without needing metabolic conversion. The HPR manufactured by Shaanxi Huatai delivers powerful anti aging benefits similar to prescription retinoids but with significantly less irritation than standard Retinol.
Do you supply Hydroxypinacolone Retinoate as a pure powder or a liquid solution?To meet diverse formulation needs, Shaanxi Huatai supplies both pure Hydroxypinacolone Retinoate powder (over 99 percent purity) for maximum cost efficiency, and a highly stable 10 percent liquid solution that is incredibly easy to incorporate into your manufacturing process.
Is your Hydroxypinacolone Retinoate oil soluble, and how should it be formulated?Yes, HPR is highly lipophilic and oil soluble. The technical formulation team at Shaanxi Huatai recommends incorporating it into the oil phase of your serums or creams. It should be added during the cool down phase at temperatures below 40 degrees Celsius to ensure maximum stability of the active ingredient.
What is the recommended usage rate for HPR in anti aging skincare formulations?When using our 10 percent HPR solution, the recommended usage rate typically ranges from 1.0 to 5.0 percent depending on the target anti aging claims. The research and development experts at Shaanxi Huatai can help you optimize the exact dosage for your specific night creams or targeted serums.
Is Hydroxypinacolone Retinoate safe for sensitive skin products?Absolutely. One of the greatest advantages of HPR is its remarkably low irritation profile. Global cosmetic formulators trust the high purity HPR from Shaanxi Huatai to develop premium anti aging products that deliver visible skin renewal without the intense peeling and redness commonly associated with traditional retinoids.
How can I ensure the stability of HPR in my cosmetic formulation?While HPR is significantly more stable than traditional retinol, it still requires proper care. Shaanxi Huatai recommends formulating with antioxidants like Vitamin E or BHT, utilizing opaque and airless packaging, and avoiding exposure to direct sunlight and high heat during the manufacturing process.
Do you provide the Certificate of Analysis (COA) and MSDS for wholesale bulk orders?Strict quality control and regulatory compliance are the standard at our manufacturing facility. Shaanxi Huatai provides comprehensive, batch specific documentation for every wholesale shipment, including the Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and purity testing reports.
What is the Minimum Order Quantity (MOQ) and why should I source directly from your factory?Shaanxi Huatai offers a highly accessible MOQ starting at just 1kg, along with 10g to 50g free testing samples. Sourcing directly from our factory in China ensures you secure highly competitive factory direct pricing, consistent batch to batch quality, and expert technical support for your formulation team.

Upgrade Your Next Bestseller Today

Stop compromising on formula stability, retinoid-induced irritation, and ingredient purity. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing anti-aging actives.

Claim your High-Purity, Odorless Sample Now and upgrade your next blockbuster SOS repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Safety Reports).

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

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Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.

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