{"id":16031,"date":"2026-09-30T02:55:46","date_gmt":"2026-09-30T02:55:46","guid":{"rendered":"https:\/\/glabridin.net\/?p=16031"},"modified":"2026-09-30T03:00:28","modified_gmt":"2026-09-30T03:00:28","slug":"pterostilbene-and-skin-aging-what-recent-research-reveals-about-cellular-senescence","status":"publish","type":"post","link":"https:\/\/glabridin.net\/ja\/pterostilbene-and-skin-aging-what-recent-research-reveals-about-cellular-senescence\/","title":{"rendered":"\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u3068\u76ae\u819a\u306e\u8001\u5316\uff1a\u7d30\u80de\u8001\u5316\u306b\u95a2\u3059\u308b\u6700\u8fd1\u306e\u7814\u7a76\u304c\u660e\u3089\u304b\u306b\u3057\u305f\u3053\u3068"},"content":{"rendered":"
\n\n

\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306f\u3001\u305d\u306e\u6297\u9178\u5316\u4f5c\u7528\u3068\u6297\u8001\u5316\u306e\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u3001\u76ae\u819a\u7814\u7a76\u3067\u7814\u7a76\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u6700\u8fd1\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u7279\u306b\u771f\u76ae\u7dda\u7dad\u82bd\u7d30\u80de\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u3001\u7d30\u80de\u8001\u5316\u306b\u95a2\u3059\u308b\u7814\u7a76\u304c\u3088\u308a\u5177\u4f53\u7684\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002 <\/p>\n\n

2025\u5e74\u306b\u767a\u8868\u3055\u308c\u305f3\u3064\u306e\u7814\u7a76\u306f\u3001\u3053\u306e\u958b\u767a\u306e\u826f\u3044\u30b9\u30ca\u30c3\u30d7\u30b7\u30e7\u30c3\u30c8\u3092\u63d0\u4f9b\u3057\u307e\u3059\u30021\u3064\u306f\u3001UVB\u8a98\u767a\u6027\u304a\u3088\u3073\u8907\u88fd\u6027\u8001\u5316\u30e2\u30c7\u30eb\u4e0b\u3067\u306e\u30d2\u30c8\u771f\u76ae\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u304a\u3051\u308b\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u3092\u8abf\u67fb\u3057\u307e\u3057\u305f\u3002\u3082\u30461\u3064\u306f\u3001UVA\u66b4\u9732\u3055\u308c\u305f\u76ae\u8102\u817a\u7d30\u80de\u3068\u7dda\u7dad\u82bd\u7d30\u80de\u3092\u8abf\u3079\u307e\u3057\u305f\u30023\u3064\u76ee\u306f\u300128\u65e5\u9593\u306e\u81e8\u5e8a\u7814\u7a76\u30670.1%\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u30b9\u30ad\u30f3\u30b1\u30a2\u30a8\u30de\u30eb\u30b7\u30e7\u30f3\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002 <\/p>\n\n

\u3053\u308c\u3089\u306e\u7814\u7a76\u3092\u5358\u4e00\u306e\u6297\u8001\u5316\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u8a3c\u62e0\u3068\u3057\u3066\u6271\u3046\u306e\u3067\u306f\u306a\u304f\u3001\u305d\u308c\u3089\u304c\u3069\u306e\u3088\u3046\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u304b\u3001\u305d\u3057\u3066\u8a3c\u62e0\u304c\u3069\u3053\u307e\u3067\u6b62\u307e\u3063\u3066\u3044\u308b\u304b\u3092\u898b\u308b\u65b9\u304c\u3088\u308a\u6709\u7528\u3067\u3059\u3002 <\/p>\n\n

\u7d30\u80de\u8001\u5316\u304c\u76ae\u819a\u8001\u5316\u306b\u95a2\u9023\u3059\u308b\u7406\u7531 <\/h2>\n\n

\u76ae\u819a\u8001\u5316\u306b\u306f\u3001\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u3001\u7d30\u80de\u6d3b\u52d5\u306e\u5909\u5316\u304c\u95a2\u4e0e\u3057\u307e\u3059\u3002\u771f\u76ae\u7dda\u7dad\u82bd\u7d30\u80de\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3084\u771f\u76ae\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306e\u4ed6\u306e\u6210\u5206\u3092\u751f\u6210\u30fb\u7dad\u6301\u3059\u308b\u305f\u3081\u3001\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306e\u4e2d\u6838\u3068\u306a\u308a\u307e\u3059\u3002 <\/p>\n\n

\u7d30\u80de\u8001\u5316\u306f\u3001\u3053\u306e\u6587\u8108\u3067\u8abf\u67fb\u3055\u308c\u3066\u3044\u308b\u751f\u7269\u5b66\u7684\u72b6\u614b\u306e1\u3064\u3067\u3059\u3002\u8001\u5316\u7d30\u80de\u306f\u3001\u5897\u6b96\u3068\u7d30\u80de\u6a5f\u80fd\u306b\u6301\u7d9a\u7684\u306a\u5909\u5316\u3092\u793a\u3057\u3001\u8001\u5316\u95a2\u9023\u306e\u5909\u5316\u306f\u3001\u52a0\u9f62\u306b\u4f34\u3046\u7d44\u7e54\u6a5f\u80fd\u4e0d\u5168\u3068\u95a2\u9023\u4ed8\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002 <\/p>\n\n

\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u3001\u7d30\u80de\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u7523\u751f\u3001\u30ec\u30c9\u30c3\u30af\u30b9\u30d0\u30e9\u30f3\u30b9\u3001\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u3092\u8abf\u7bc0\u3059\u308b\u305f\u3081\u3001\u3053\u306e\u72b6\u6cc1\u306e\u4e00\u90e8\u3067\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u8cea\u306e\u4f4e\u4e0b\u306f\u3001\u7d30\u80de\u6a5f\u80fd\u4e0d\u5168\u3092\u4f34\u3046\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 <\/p>\n\n

\u3053\u308c\u306f\u3001\u6297\u9178\u5316\u6d3b\u6027\u3060\u3051\u3088\u308a\u3082\u3001\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u3092\u7814\u7a76\u3059\u308b\u305f\u3081\u306e\u3088\u308a\u6709\u7528\u306a\u67a0\u7d44\u307f\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002\u7814\u7a76\u8005\u306f\u3001\u5316\u5408\u7269\u304c\u6d3b\u6027\u9178\u7d20\u7a2e\u3092\u6e1b\u5c11\u3055\u305b\u308b\u304b\u3069\u3046\u304b\u3060\u3051\u3092\u5c0b\u306d\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u8001\u5316\u306b\u95a2\u9023\u3059\u308b\u7d30\u80de\u306e\u72b6\u614b\u3092\u5909\u5316\u3055\u305b\u308b\u304b\u3069\u3046\u304b\u3092\u8abf\u3079\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 <\/p>\n\n

\u6700\u8fd1\u306e\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u7814\u7a76\u3067\u898b\u3064\u304b\u3063\u305f\u3053\u3068 <\/h2>\n\n

\u306b\u767a\u8868\u3055\u308c\u305f\u7814\u7a76 \u30d5\u30ed\u30f3\u30c6\u30a3\u30a2\u30ba\u30fb\u30a4\u30f3\u30fb\u30d5\u30a1\u30fc\u30de\u30b3\u30ed\u30b8\u30fc<\/em> 2025\u5e7412\u6708\u306b\u3001UVB\u8a98\u767a\u6027\u306e\u6025\u6027\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u304a\u3088\u3073\u8907\u88fd\u6027\u8001\u5316\u30e2\u30c7\u30eb\u3092\u4f7f\u7528\u3057\u305f\u30d2\u30c8\u771f\u76ae\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u304a\u3051\u308b\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u3092\u8abf\u67fb\u3057\u307e\u3057\u305f\u3002\u7814\u7a76\u8005\u3089\u306f\u3001\u8001\u5316\u95a2\u9023\u306e\u03b2-\u30ac\u30e9\u30af\u30c8\u30b7\u30c0\u30fc\u30bc\u3001p16\u304a\u3088\u3073p21\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u767a\u73fe\u3001\u304a\u3088\u3073\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u306e\u3044\u304f\u3064\u304b\u306e\u6e2c\u5b9a\u5024\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001UVB\u66b4\u9732\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u3067\u5c40\u6240\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u3092\u30c6\u30b9\u30c8\u3057\u307e\u3057\u305f\u3002 \uff08Zhou et al., 2025\uff09<\/span>. <\/p>\n\n

\u4e21\u65b9\u306e\u7dda\u7dad\u82bd\u7d30\u80de\u30e2\u30c7\u30eb\u306b\u304a\u3044\u3066\u3001\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306f\u3001SA-\u03b2-gal\u6d3b\u6027\u306e\u4f4e\u4e0b\u304a\u3088\u3073p16\u304a\u3088\u3073p21\u30ec\u30d9\u30eb\u306e\u4f4e\u4e0b\u3001\u306a\u3089\u3073\u306b\u30b3\u30e9\u30fc\u30b2\u30f3I\u304a\u3088\u3073III\u767a\u73fe\u306e\u5897\u52a0\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u51e6\u7406\u3055\u308c\u305f\u7d30\u80de\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u5f62\u614b\u304a\u3088\u3073\u819c\u96fb\u4f4d\u306e\u6539\u5584\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2ROS\u306e\u4f4e\u4e0b\u3001\u304a\u3088\u3073\u57fa\u790e\u547c\u5438\u3001ATP\u7523\u751f\u3001\u6700\u5927\u547c\u5438\u306e\u5897\u52a0\u3082\u793a\u3057\u307e\u3057\u305f\u3002TOM20\/LC3\u306e\u5171\u5c40\u5728\u5316\u306e\u5897\u52a0\u306f\u3001\u30df\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u5897\u5f37\u3068\u89e3\u91c8\u3055\u308c\u307e\u3057\u305f\u3002\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u3067\u306f\u3001\u5c40\u6240\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u56de\u5fa9\u3068\u771f\u76ae\u306e\u539a\u3055\u306e\u5897\u52a0\u3001\u304a\u3088\u3073p21\u767a\u73fe\u306e\u4f4e\u4e0b\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3057\u305f\u3002 <\/p>\n\n

\u3053\u306e\u7814\u7a76\u306e\u610f\u7fa9\u306f\u3001\u3053\u308c\u3089\u306e\u767a\u898b\u306e\u95a2\u9023\u6027\u306b\u3042\u308a\u307e\u3059\u3002\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306f\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u5236\u5fa1\u3059\u308b\u80fd\u529b\u306b\u3064\u3044\u3066\u306e\u307f\u8a55\u4fa1\u3055\u308c\u3066\u3044\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u7814\u7a76\u8005\u3089\u306f\u3001 \u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u54c1\u8cea\u7ba1\u7406\u3068\u771f\u76ae\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u8001\u5316\u95a2\u9023\u306e\u5909\u5316<\/strong>. <\/p>\n\n

\u3092\u95a2\u9023\u4ed8\u3051\u307e\u3057\u305f\u3002 \u3053\u308c\u306b\u3088\u308a\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u54c1\u8cea\u306f\u3001\u3055\u3089\u306a\u308b\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u7814\u7a76\u306e\u8208\u5473\u6df1\u3044\u5206\u91ce\u3068\u306a\u308a\u307e\u3059\u3002<\/strong> \u3057\u304b\u3057\u3001\u5c40\u6240\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u304c\u30d2\u30c8\u306e\u76ae\u819a\u306e\u7d30\u80de\u8001\u5316\u3092\u9006\u8ee2\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3053\u3068\u3092\u78ba\u7acb\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002 <\/p>\n\n

\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u5b9f\u9a13\u306fin vitro\u3067\u884c\u308f\u308c\u307e\u3057\u305f\u304c\u3001in vivo\u306e\u7814\u7a76\u3067\u306f\u30de\u30a6\u30b9\u304c\u4f7f\u7528\u3055\u308c\u307e\u3057\u305f\u3002 \u56fd\u969b\u5316\u7ca7\u54c1\u79d1\u5b66\u30b8\u30e3\u30fc\u30ca\u30eb<\/em>2\u756a\u76ee\u306e2025\u5e74\u306e\u7814\u7a76\u306f\u3001 \u3067\u767a\u8868\u3055\u308c\u3001\u76ae\u819a\u8001\u5316\u306e\u7570\u306a\u308b\u5074\u9762\u3092\u8abf\u3079\u307e\u3057\u305f\u3002UVA\u66b4\u9732\u3055\u308c\u305f\u76ae\u8102\u817a\u7d30\u80de\u306b\u304a\u3044\u3066\u3001\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306fROS\u3092\u6e1b\u3089\u3057\u3001\u8102\u8cea\u5408\u6210\u3092\u5897\u52a0\u3055\u305b\u307e\u3057\u305f\u3002UVA\u66b4\u9732\u3055\u308c\u305f\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u304a\u3044\u3066\u3001ROS\u3092\u6e1b\u3089\u3057\u3001\u30b3\u30e9\u30fc\u30b2\u30f3I\u304a\u3088\u3073III\u3092\u5897\u52a0\u3055\u305b\u307e\u3057\u305f\u3002\u3053\u306e\u7814\u7a76\u306f\u307e\u305f\u3001F-\u30a2\u30af\u30c1\u30f3\u5206\u5e03\u304a\u3088\u3073Nrf2\u3084Sirt6\u306a\u3069\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306e\u5909\u5316\u3092\u5831\u544a\u3057\u307e\u3057\u305f\u3002<\/span>. <\/p>\n\n

\uff08Zhong et al., 2025\uff09 <\/p>\n\n

\u3053\u306e\u7814\u7a76\u306f\u3001\u771f\u76ae\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u8001\u5316\u3092\u8d85\u3048\u3066\u7814\u7a76\u3092\u5e83\u3052\u307e\u3059\u3002\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306f\u3001\u7d2b\u5916\u7dda\u95a2\u9023\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3059\u308b\u76ae\u8102\u817a\u304a\u3088\u3073\u771f\u76ae\u306e\u4e21\u65b9\u306e\u5fdc\u7b54\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u308c\u3089\u306e\u767a\u898b\u3082\u9577\u671f\u7684\u306a\u30d2\u30c8\u4ecb\u5165\u3067\u306f\u306a\u304f\u3001\u5b9f\u9a13\u30e2\u30c7\u30eb\u304b\u3089\u306e\u3082\u306e\u3067\u3059\u3002 <\/h2>\n\n

\u7d30\u80de\u6240\u898b\u304b\u3089\u30d2\u30c8\u306e\u76ae\u819a\u3078\u306e\u5f71\u97ff\u307e\u3067 <\/p>\n\n

\u3088\u308a\u96e3\u3057\u3044\u8cea\u554f\u306f\u3001\u3053\u308c\u3089\u306e\u751f\u7269\u5b66\u7684\u89b3\u5bdf\u304c\u30d2\u30c8\u306e\u76ae\u819a\u306e\u6e2c\u5b9a\u53ef\u80fd\u306a\u5909\u5316\u3068\u95a2\u9023\u4ed8\u3051\u3089\u308c\u308b\u304b\u3069\u3046\u304b\u3067\u3059\u3002 2025\u5e74\u306e\u81e8\u5e8a\u7814\u7a76\u3067\u306f\u3001<\/strong> 1%\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3 \u3092\u542b\u3080\u30b9\u30ad\u30f3\u30b1\u30a2\u30a8\u30de\u30eb\u30b7\u30e7\u30f3\u309231\u4eba\u306e\u53c2\u52a0\u8005\u3067\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u8a66\u9a13\u306f\u300128\u65e5\u9593\u3001\u4e8c\u91cd\u76f2\u691c\u3001\u7247\u5074\u30c7\u30b6\u30a4\u30f3\u3092\u4f7f\u7528\u3057\u3001\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u30a8\u30de\u30eb\u30b7\u30e7\u30f3\u3068\u5bfe\u7167\u30a8\u30de\u30eb\u30b7\u30e7\u30f3\u3092\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002\u6e2c\u5b9a\u306b\u306f\u3001\u76ae\u819a\u306e\u5f3e\u529b\u6027\u3068\u30cf\u30ea\u3001\u3057\u308f\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u3001\u8868\u76ae\u306e\u539a\u3055\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u95a2\u9023\u86cd\u5149\u3001\u5f3e\u6027\u7dda\u7dad\u86cd\u5149\u3001\u304a\u3088\u3073\u771f\u76ae\u8868\u76ae\u63a5\u5408\u90e8\u304c\u542b\u307e\u308c\u307e\u3057\u305f\u3002<\/span>. <\/p>\n\n

\uff08Cen et al., 2025\uff09 <\/p>\n\n

\u7814\u7a76\u8005\u3089\u306f\u3001\u5bfe\u7167\u30a8\u30de\u30eb\u30b7\u30e7\u30f3\u3068\u6bd4\u8f03\u3057\u3066\u3001\u5f3e\u529b\u6027\u3001\u30cf\u30ea\u3001\u3057\u308f\u306e\u6e2c\u5b9a\u5024\u3001\u8868\u76ae\u306e\u539a\u3055\u3001\u304a\u3088\u3073\u753b\u50cf\u95a2\u9023\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u304a\u3088\u3073\u5f3e\u6027\u7dda\u7dad\u306e\u6e2c\u5b9a\u5024\u3092\u542b\u3080\u3001\u3053\u308c\u3089\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u306e\u3044\u304f\u3064\u304b\u306e\u9855\u8457\u306a\u6539\u5584\u3092\u5831\u544a\u3057\u307e\u3057\u305f\u3002 \u3053\u308c\u306b\u3088\u308a\u3001\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306f\u3001\u5b9f\u9a13\u5ba4\u306e\u7814\u7a76\u3092\u88dc\u5b8c\u3059\u308b\u30d2\u30c8\u81e8\u5e8a\u30c7\u30fc\u30bf\u30dd\u30a4\u30f3\u30c8\u304c\u5f97\u3089\u308c\u307e\u3057\u305f\u3002<\/strong>\u3053\u308c\u3089\u306e\u81e8\u5e8a\u7684\u5909\u5316\u304c\u7d30\u80de\u8001\u5316\u307e\u305f\u306f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u54c1\u8cea\u306e\u5909\u5316\u306b\u3088\u3063\u3066\u7279\u7570\u7684\u306b\u5f15\u304d\u8d77\u3053\u3055\u308c\u305f\u3053\u3068\u3092\u78ba\u7acb\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093 <\/p>\n\n

\u3001\u306a\u305c\u306a\u3089\u3053\u308c\u3089\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u81e8\u5e8a\u7814\u7a76\u3067\u306f\u76f4\u63a5\u6e2c\u5b9a\u3055\u308c\u306a\u304b\u3063\u305f\u304b\u3089\u3067\u3059\u3002 <\/p>\n\n

\u3053\u306e\u7814\u7a76\u306b\u306f\u3001\u7d50\u679c\u3092\u89e3\u91c8\u3059\u308b\u969b\u306b\u91cd\u8981\u306a\u9650\u754c\u3082\u3042\u308a\u307e\u3059\u300231\u4eba\u306e\u53c2\u52a0\u8005\u304c\u95a2\u4e0e\u3057\u300128\u65e5\u9593\u7d9a\u304d\u3001\u30c6\u30b9\u30c8\u3055\u308c\u305f\u6750\u6599\u306f\u7279\u5b9a\u306e0.1%\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u30a8\u30de\u30eb\u30b7\u30e7\u30f3\u3067\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u3053\u306e\u7814\u7a76\u306f\u5e83\u5dde\u8def\u71d5\u5316\u7ca7\u54c1\u6709\u9650\u516c\u53f8\u306b\u3088\u3063\u3066\u8cc7\u91d1\u63d0\u4f9b\u3055\u308c\u3001\u6570\u4eba\u306e\u8457\u8005\u306f\u540c\u793e\u307e\u305f\u306f\u95a2\u9023\u7d44\u7e54\u306b\u96c7\u7528\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002 \u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306e\u30d2\u30c8\u7814\u7a76\u306b\u3068\u3063\u3066\u3001\u3053\u308c\u3089\u306e\u8a73\u7d30\u306f\u91cd\u8981\u3067\u3059\u3002\u7d50\u679c\u306f\u95a2\u9023\u6027\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u308c\u3089\u306f\u9577\u671f\u7684\u306a\u76ae\u819a\u8001\u5316\u306e\u5b8c\u5168\u306a\u8a3c\u62e0\u3067\u306f\u306a\u304f\u3001<\/strong>. <\/p>\n\n

\u521d\u671f\u306e\u81e8\u5e8a\u30c7\u30fc\u30bf\u30dd\u30a4\u30f3\u30c8\u3092\u8868\u3057\u307e\u3059\u3002 <\/h2>\n\n

\u5316\u7ca7\u54c1\u6709\u52b9\u6210\u5206\u958b\u767a\u306b\u304a\u3051\u308b\u610f\u5473 <\/p>\n\n

\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306f\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3001\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u8001\u5316\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u95a2\u9023\u5fdc\u7b54\u3001\u304a\u3088\u3073\u6e2c\u5b9a\u53ef\u80fd\u306a\u76ae\u819a\u30d1\u30e9\u30e1\u30fc\u30bf\u3068\u3044\u3063\u305f\u3001\u3044\u304f\u3064\u304b\u306e\u95a2\u9023\u3059\u308b\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3092\u901a\u3058\u3066\u8abf\u67fb\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3092\u500b\u5225\u306e\u4e3b\u5f35\u3068\u3057\u3066\u6271\u3046\u5fc5\u8981\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u308c\u3089\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u751f\u7269\u5b66\u7684\u8a66\u9a13\u304b\u3089\u88fd\u54c1\u8a55\u4fa1\u306b\u81f3\u308b\u307e\u3067\u3001\u6709\u52b9\u6210\u5206\u306e\u6319\u52d5\u306b\u3064\u3044\u3066\u3088\u308a\u4e00\u8cab\u6027\u306e\u3042\u308b\u5168\u4f53\u50cf\u3092\u69cb\u7bc9\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002 <\/p>\n\n

\u3057\u304b\u3057\u3001\u51e6\u65b9\u8005\u306b\u3068\u3063\u3066\u306f\u3001\u5b9f\u9a13\u5ba4\u3067\u306e\u6d3b\u52d5\u306f\u305d\u306e\u30d7\u30ed\u30bb\u30b9\u306e\u307b\u3093\u306e\u4e00\u90e8\u306b\u3059\u304e\u307e\u305b\u3093\u3002 <\/p>\n\n

1%\u306e\u81e8\u5e8a\u8a66\u9a13\u306f\u3001\u5b9a\u7fa9\u3055\u308c\u305f\u30a8\u30de\u30eb\u30b8\u30e7\u30f3\u3068\u5857\u5e03\u30d7\u30ed\u30c8\u30b3\u30eb\u3092\u7528\u3044\u3066\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3092\u5225\u306e\u6fc3\u5ea6\u3084\u88fd\u5264\u30b7\u30b9\u30c6\u30e0\u306b\u5358\u7d14\u306b\u8ee2\u9001\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002 \u6eb6\u89e3\u6027\u3001\u5b89\u5b9a\u6027\u3001\u62c5\u4f53\u7d44\u6210\u3001\u52a0\u5de5\u3001\u304a\u3088\u3073\u76ae\u819a\u3078\u306e\u66dd\u9732\u306f\u3059\u3079\u3066\u3001\u6700\u7d42\u88fd\u54c1\u306b\u304a\u3051\u308b\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306e\u6027\u80fd\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/strong> <\/p>\n\n

\u3053\u3053\u3067\u3001\u539f\u6599\u7814\u7a76\u3068\u88fd\u5264\u958b\u767a\u304c\u51fa\u4f1a\u3044\u307e\u3059\u3002\u6709\u671b\u306a\u751f\u7269\u5b66\u7684\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306f\u3055\u3089\u306a\u308b\u958b\u767a\u3092\u6b63\u5f53\u5316\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u6700\u7d42\u7684\u306a\u8a55\u4fa1\u306f\u3001\u305d\u306e\u6210\u5206\u304c\u5b9f\u7528\u7684\u306a\u88fd\u5264\u3067\u4e00\u8cab\u3057\u3066\u6027\u80fd\u3092\u767a\u63ee\u3059\u308b\u304b\u3069\u3046\u304b\u3001\u305d\u3057\u3066\u305d\u306e\u6027\u80fd\u304c\u30d2\u30c8\u306e\u30c7\u30fc\u30bf\u306b\u3088\u3063\u3066\u88cf\u4ed8\u3051\u3089\u308c\u308b\u304b\u3069\u3046\u304b\u306b\u4f9d\u7136\u3068\u3057\u3066\u4f9d\u5b58\u3057\u307e\u3059\u3002 <\/p>\n\n

\u73fe\u5728\u306e\u8a3c\u62e0\u304c\u307e\u3060\u5fc5\u8981\u3068\u3057\u3066\u3044\u308b\u3082\u306e <\/h2>\n\n

\u6700\u8fd1\u306e\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306b\u95a2\u3059\u308b\u6587\u732e\u306f\u307e\u3059\u307e\u3059\u8208\u5473\u6df1\u3044\u3082\u306e\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u307e\u3060\u6bd4\u8f03\u7684\u521d\u671f\u6bb5\u968e\u3067\u3059\u3002 <\/p>\n\n

2025\u5e7412\u6708\u306e\u7dda\u7dad\u82bd\u7d30\u80de\u7814\u7a76\u306f\u3001\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u54c1\u8cea\u3001\u304a\u3088\u3073\u8001\u5316\u95a2\u9023\u306e\u5909\u5316\u3068\u306e\u9593\u306e\u8a73\u7d30\u306a\u5b9f\u9a13\u7684\u95a2\u9023\u6027\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002UVA\u7814\u7a76\u306f\u3001\u74b0\u5883\u30b9\u30c8\u30ec\u30b9\u306b\u3055\u3089\u3055\u308c\u305f\u76ae\u8102\u817a\u7d30\u80de\u304a\u3088\u3073\u7dda\u7dad\u82bd\u7d30\u80de\u304b\u3089\u306e\u8a3c\u62e0\u3092\u8ffd\u52a0\u3057\u307e\u3059\u3002\u81e8\u5e8a\u7814\u7a76\u306f\u30010.1%\u306e\u5c40\u6240\u30a8\u30de\u30eb\u30b8\u30e7\u30f3\u3092\u4f7f\u7528\u3057\u305f\u521d\u671f\u306e\u30d2\u30c8\u306e\u7d50\u679c\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002 <\/p>\n\n

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\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u304c\u76ae\u819a\u306e\u8001\u5316\u3068\u9577\u5bff\u306b\u95a2\u3059\u308b\u8b70\u8ad6\u306b\u3055\u3089\u306b\u9032\u3080\u5834\u5408\u3001\u305d\u306e\u533a\u5225\u306f\u91cd\u8981\u306b\u306a\u308a\u307e\u3059\u3002 <\/p>\n\n

\u53c2\u8003\u6587\u732e <\/h2>\n\n
\n\n

1.<\/strong> \u5468X\u3001\u738bN\u3001\u9b4fJ\u4ed6\u3002(2025\u5e74)\u3002 \u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u54c1\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u30d2\u30c8\u76ae\u819a\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u8001\u5316\u3092\u8efd\u6e1b\u3057\u307e\u3059\u3002<\/em> \u30d5\u30ed\u30f3\u30c6\u30a3\u30a2\u30ba\u30fb\u30a4\u30f3\u30fb\u30d5\u30a1\u30fc\u30de\u30b3\u30ed\u30b8\u30fc<\/em>, 16, 1732154.
DOI: 10.3389\/fphar.2025.1732154<\/span> <\/p>\n\n

2.<\/strong> \u4e2dY\u3001\u738bQ\u3001\u738bY\u3001\u53f6R\u3001\u675cL\u3001\u80e1F\u3002(2025\u5e74)\u3002 \u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\uff1a\u76ae\u8102\u817a\u7d30\u80de\u304a\u3088\u3073\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u304a\u3051\u308b\u6297\u8001\u5316\u306e\u305f\u3081\u306e\u5929\u7136\u5316\u5408\u7269\u3002<\/em> \u56fd\u969b\u5316\u7ca7\u54c1\u79d1\u5b66\u30b8\u30e3\u30fc\u30ca\u30eb<\/em>\u300147(5)\u3001902\u2013915\u3002
DOI: 10.1111\/ics.13078<\/span> <\/p>\n\n

3.<\/strong> \u5c91Z\u3001\u9648Z\u3001\u738bD\u4ed6\u3002(2025\u5e74)\u3002 1% \u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3 \u30b9\u30ad\u30f3\u30b1\u30a2\u30a8\u30de\u30eb\u30b8\u30e7\u30f3\u306e\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u52b9\u679c\uff1a28\u65e5\u9593\u306e\u81e8\u5e8a\u8a66\u9a13\u3002<\/em> \u76ae\u819a\u79d1\u5b66\u3068\u7f8e\u5bb9\u6280\u8853\u30b8\u30e3\u30fc\u30ca\u30eb<\/em>\u30012(2)\u3001100083\u3002
DOI: 10.1016\/j.jdsct.2025.100083<\/span> <\/p>\n\n<\/div>\n\n<\/div>","protected":false},"excerpt":{"rendered":"

\u30d7\u30c6\u30ed\u30b9\u30c1\u30eb\u30d9\u30f3\u306f\u3001\u305d\u306e\u6297\u9178\u5316\u4f5c\u7528\u3068\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u306e\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u3001\u76ae\u819a\u306e\u7814\u7a76\u3067\u7814\u7a76\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u6700\u8fd1\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u7279\u306b\u76ae\u819a\u306e\u2026\u306b\u95a2\u3059\u308b\u7814\u7a76\u50cf\u304c\u3088\u308a\u5177\u4f53\u7684\u306b\u306a\u3063\u3066\u304d\u3066\u3044\u307e\u3059\u3002<\/p>","protected":false},"author":8,"featured_media":16032,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-16031","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nPterostilbene and Skin Aging: What Recent Research Reveals About Cellular Senescence - Huatai Bio<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/glabridin.net\/ja\/pterostilbene-and-skin-aging-what-recent-research-reveals-about-cellular-senescence\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pterostilbene and Skin Aging: What Recent Research Reveals About Cellular Senescence\" \/>\n<meta property=\"og:description\" content=\"Pterostilbene has been studied in skin research for its antioxidant and anti-aging potential. 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