{"id":16038,"date":"2026-10-08T08:41:00","date_gmt":"2026-10-08T08:41:00","guid":{"rendered":"https:\/\/glabridin.net\/?p=16038"},"modified":"2026-10-08T08:41:01","modified_gmt":"2026-10-08T08:41:01","slug":"from-licorice-source-to-cosmetic-ingredient-what-traceability-adds-to-glabridin-sourcing","status":"publish","type":"post","link":"https:\/\/glabridin.net\/fr\/from-licorice-source-to-cosmetic-ingredient-what-traceability-adds-to-glabridin-sourcing\/","title":{"rendered":"De la source de r\u00e9glisse \u00e0 l'ingr\u00e9dient cosm\u00e9tique : ce que la tra\u00e7abilit\u00e9 ajoute \u00e0 l'approvisionnement en glabridine"},"content":{"rendered":"
\n\n

Un \u00e9chantillon de glabridine peut passer une \u00e9valuation initiale sans en dire long sur ce qui se passera six mois plus tard. <\/p>\n\n

L'analyse est acceptable. L'apparence est conforme aux sp\u00e9cifications. L'essai de formulation fonctionne. <\/p>\n\n

Ensuite, un nouveau lot arrive. <\/p>\n\n

Si le mat\u00e9riau semble ou se comporte diff\u00e9remment, la r\u00e9ponse habituelle est de v\u00e9rifier d'abord l'ingr\u00e9dient fini. Comparer le COA. R\u00e9p\u00e9ter l'analyse. Examiner l'\u00e9chantillon approuv\u00e9. <\/p>\n\n

Avec les ingr\u00e9dients botaniques, il y a un autre endroit o\u00f9 chercher : en amont.<\/strong> <\/p>\n\n

La glabridine commence par la r\u00e9glisse, mais la r\u00e9glisse utilis\u00e9e pour l'extraction fait elle-m\u00eame partie de la cha\u00eene d'approvisionnement. Les lots de mati\u00e8res premi\u00e8res changent. Les sources agricoles peuvent changer. La r\u00e9colte, le stockage et la transformation se situent entre la plante et l'ingr\u00e9dient fini. <\/p>\n\n

Cette histoire ne rend pas l'ingr\u00e9dient meilleur en soi. Elle devient utile lorsqu'un lot doit \u00eatre compris. <\/p>\n\n

De la r\u00e9glisse \u00e0 un ingr\u00e9dient d\u00e9fini <\/h2>\n\n

La glabridine est un flavono\u00efde caract\u00e9ristique que l'on trouve dans la r\u00e9glisse, en particulier Glycyrrhiza glabra<\/em>. Sa chimie et ses propri\u00e9t\u00e9s biologiques ont \u00e9t\u00e9 largement pass\u00e9es en revue (Simmler et al., 2013). <\/p>\n\n

Pour un usage commercial, cependant, \"d\u00e9riv\u00e9 de la r\u00e9glisse\" n'est que le point de d\u00e9part.<\/strong> <\/p>\n\n

Une fois que la mati\u00e8re v\u00e9g\u00e9tale entre en production, l'extraction et la purification d\u00e9terminent la composition de l'actif r\u00e9sultant. Le mat\u00e9riau fini est ensuite fourni selon une sp\u00e9cification et une m\u00e9thode analytique d\u00e9finies. <\/p>\n\n

C'est une des raisons pour lesquelles un fournisseur de glabridine<\/strong> ne peut \u00eatre \u00e9valu\u00e9 uniquement par la source botanique ou le premier \u00e9chantillon. <\/p>\n\n

Deux mat\u00e9riaux peuvent tous deux \u00eatre d\u00e9crits comme de la glabridine d\u00e9riv\u00e9e de la r\u00e9glisse, mais diff\u00e9rer par leur dosage, leur forme physique, leur historique de fabrication et leur documentation justificative. <\/p>\n\n

Le premier \u00e9chantillon nous indique si le mat\u00e9riau peut fonctionner. L'approvisionnement \u00e0 long terme soul\u00e8ve une question diff\u00e9rente : le m\u00eame mat\u00e9riau d\u00e9fini peut-il \u00eatre maintenu sur les lots suivants ?<\/strong> <\/p>\n\n

Quand la tra\u00e7abilit\u00e9 devient utile <\/h2>\n\n

La tra\u00e7abilit\u00e9 n'a pas besoin d'\u00eatre compliqu\u00e9e pour \u00eatre utile. <\/p>\n\n

Au niveau pratique, les liens importants sont entre la mati\u00e8re premi\u00e8re, le lot de production, le r\u00e9sultat analytique et l'exp\u00e9dition finale. <\/p>\n\n

Consid\u00e9rez une situation simple. Deux lots pr\u00e9sentent des r\u00e9sultats d'analyse diff\u00e9rents. <\/p>\n\n

Le COA vous indique ce qui a \u00e9t\u00e9 mesur\u00e9 dans chaque lot. Il ne vous dit pas n\u00e9cessairement ce qui a chang\u00e9 avant que le mat\u00e9riau n'atteigne le laboratoire. <\/p>\n\n

Si le lot fini peut \u00eatre li\u00e9 au lot de mati\u00e8re premi\u00e8re entrant et aux enregistrements de production, il y a une base pour enqu\u00eater sur la diff\u00e9rence. <\/p>\n\n

Il en va de m\u00eame lorsqu'une source agricole change. <\/p>\n\n

Une source ou un lot de mati\u00e8re premi\u00e8re diff\u00e9rent n'est pas automatiquement un probl\u00e8me de qualit\u00e9. Ce qui importe, c'est que le changement soit document\u00e9 et \u00e9valu\u00e9, et que le mat\u00e9riau r\u00e9sultant continue de r\u00e9pondre \u00e0 la sp\u00e9cification convenue. <\/p>\n\n

Pour les ingr\u00e9dients botaniques, c'est une approche plus pratique de la continuit\u00e9 de l'approvisionnement que de supposer que la source agricole restera compl\u00e8tement inchang\u00e9e. <\/p>\n\n

La puret\u00e9 a toujours besoin d'un contexte analytique <\/h2>\n\n

La m\u00eame r\u00e9flexion s'applique \u00e0 la puret\u00e9 de la glabridine. <\/p>\n\n

Une sp\u00e9cification de 98 % ou 99 % est utile, mais le chiffre n'est qu'une partie de l'information. La m\u00e9thode analytique et les r\u00e9sultats des lots individuels fournissent le contexte n\u00e9cessaire pour l'interpr\u00e9ter. <\/p>\n\n

Des m\u00e9thodes HPLC et HPTLC ont \u00e9t\u00e9 rapport\u00e9es pour d\u00e9terminer la glabridine dans les Glycyrrhiza glabra<\/em> extraits (Viswanathan et Mukne, 2016). <\/p>\n\n

Une analyse Intertek d'un \u00e9chantillon de glabridine Huatai a rapport\u00e9 99,3 % de glabridine par HPLC, avec une aire relative de 99,7 %.<\/strong> <\/p>\n\n

Ce r\u00e9sultat appartient \u00e0 l'\u00e9chantillon test\u00e9. Il ne doit pas \u00eatre consid\u00e9r\u00e9 comme une preuve que chaque lot futur produira exactement le m\u00eame r\u00e9sultat. <\/p>\n\n

Pour l'approvisionnement commercial, la question la plus utile est de savoir si les lots successifs restent dans les limites de la sp\u00e9cification convenue. C'est le c\u00f4t\u00e9 pratique de la puret\u00e9 de la glabridine<\/strong>. Le pourcentage est important, mais sa capacit\u00e9 \u00e0 \u00eatre surveill\u00e9 de mani\u00e8re coh\u00e9rente au fil du temps l'est aussi. <\/p>\n\n

L'ingr\u00e9dient doit toujours fonctionner dans la formulation <\/h2>\n\n

La tra\u00e7abilit\u00e9 et les donn\u00e9es analytiques ne suppriment pas la n\u00e9cessit\u00e9 d'\u00e9valuer la qualit\u00e9 commerciale r\u00e9elle. <\/p>\n\n

La glabridine peut \u00eatre fournie sous diff\u00e9rentes formes en fonction de la formulation pr\u00e9vue. Huatai fournit des qualit\u00e9s solubles dans l'alcool \u00e0 40 %, 90 %, 98 % et 99 %, une poudre hydrosoluble \u00e0 10 %, un liquide hydrosoluble \u00e0 1\u20135 % et une qualit\u00e9 liposoluble \u00e0 90 %. La poudre hydrosoluble \u00e0 10 % utilise un complexe d'inclusion HP-b\u00eata-CD. <\/p>\n\n

Le m\u00eame actif ne se comporte pas n\u00e9cessairement de la m\u00eame mani\u00e8re dans tous les syst\u00e8mes de formulation. <\/p>\n\n

Une formule \u00e0 base d'eau et une formule \u00e0 base d'huile peuvent n\u00e9cessiter des qualit\u00e9s diff\u00e9rentes ou des approches d'incorporation diff\u00e9rentes. Cela rend la solubilit\u00e9 de la glabridine<\/strong> pertinente lors de la s\u00e9lection des ingr\u00e9dients, et non seulement apr\u00e8s l'apparition de probl\u00e8mes de formulation. <\/p>\n\n

Huatai a \u00e9valu\u00e9 sa glabridine liposoluble \u00e0 90 % dans l'huile de cam\u00e9lia. Lors d'une observation de sept jours, le mat\u00e9riau est rest\u00e9 uniform\u00e9ment dispers\u00e9, tandis que la glabridine standard utilis\u00e9e pour la comparaison a montr\u00e9 une s\u00e9dimentation. <\/p>\n\n

L'observation est sp\u00e9cifique au mat\u00e9riau et au syst\u00e8me test\u00e9s. Elle n'\u00e9tablit pas le m\u00eame comportement dans toutes les huiles cosm\u00e9tiques ou formulations finies. <\/p>\n\n

Ce que le fournisseur doit garder sous contr\u00f4le <\/h2>\n\n

Huatai s'approvisionne en mati\u00e8res premi\u00e8res de r\u00e9glisse dans les zones de culture du Kirghizistan et de l'Ouzb\u00e9kistan et les transforme dans sa base de production \u00e0 Yangling, en Chine. <\/p>\n\n

Conna\u00eetre la source est utile. \u00catre capable de relier cette source au lot de production, \u00e0 la sp\u00e9cification et aux enregistrements analytiques est plus utile. <\/p>\n\n

Cela devient de plus en plus important apr\u00e8s l'approbation de l'\u00e9chantillon initial. <\/p>\n\n

Un ingr\u00e9dient botanique passera par diff\u00e9rents lots de mati\u00e8res premi\u00e8res et lots de production au cours de sa vie commerciale. La source agricole peut \u00e9galement changer. Le r\u00f4le du fournisseur n'est pas d'emp\u00eacher tout changement, mais de maintenir ces changements suffisamment contr\u00f4l\u00e9s pour que le mat\u00e9riau fourni au client reste d\u00e9fini et compr\u00e9hensible. <\/p>\n\n

Pour la glabridine, la tra\u00e7abilit\u00e9 n'est donc pas simplement un moyen de documenter d'o\u00f9 vient la r\u00e9glisse. Elle fait partie de la connaissance de ce qui se cache derri\u00e8re le lot qui parvient finalement au laboratoire de formulation. <\/p>\n\n

R\u00e9f\u00e9rences <\/h2>\n\n

\n Simmler, C., Pauli, G. F., & Jaki, B. U. (2013). Phytochimie et propri\u00e9t\u00e9s biologiques de la glabridine<\/em>Fitoterapia, 90, 160\u2013184.\n<\/p>\n\n

\n Viswanathan, V., & Mukne, A. P. (2016). D\u00e9veloppement et validation de m\u00e9thodes HPLC et HPTLC pour l'estimation de la glabridine dans des extraits de Glycyrrhiza glabra<\/em>Journal of AOAC International, 99(2), 374\u2013379.\n<\/p>\n\n

\n Liens de r\u00e9f\u00e9rence : https:\/\/doi.org\/10.1016\/j.fitote.2013.06.008\n<\/p>\n\n

\n https:\/\/academic.oup.com\/jaoac\/article\/99\/2\/374\/5655221\n<\/p>\n\n<\/div>\n\n<\/div>","protected":false},"excerpt":{"rendered":"

Un \u00e9chantillon de glabridine peut passer une \u00e9valuation initiale sans en dire long sur ce qui se passera six mois plus tard. L'essai est acceptable. L'apparence est\u2026<\/p>","protected":false},"author":8,"featured_media":16039,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-16038","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nFrom Licorice Source to Cosmetic Ingredient: What Traceability Adds to Glabridin Sourcing - Huatai Bio<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/glabridin.net\/fr\/from-licorice-source-to-cosmetic-ingredient-what-traceability-adds-to-glabridin-sourcing\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"From Licorice Source to Cosmetic Ingredient: What Traceability Adds to Glabridin Sourcing\" \/>\n<meta property=\"og:description\" content=\"A Glabridin sample can pass an initial evaluation without telling much about what will happen six months later. 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